Primary Biliary Cholangitis, formerly known as Primary Biliary Cirrhosis, is a chronic liver disease characterized by the progressive destruction of the bile ducts. This results in the accumulation of bile in the liver, leading to liver damage over time. It predominantly affects middle-aged women.

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Primary Biliary Cholangitis FAQ


What is Primary Biliary Cholangitis?

Primary Biliary Cholangitis is a chronic liver disease that causes damage to the small bile ducts within the liver.

Who does Primary Biliary Cholangitis affect?

It predominantly affects middle-aged women, but men can also develop this condition.

What are the symptoms of Primary Biliary Cholangitis?

Common symptoms include fatigue, itchy skin, abdominal pain, and dry eyes and mouth.

How is Primary Biliary Cholangitis diagnosed?

Diagnosis involves blood tests, liver function tests, imaging studies, and sometimes a liver biopsy.

Is there a cure for Primary Biliary Cholangitis?

While there's no cure, medications can help slow the progression of the disease and manage symptoms.

What are the possible complications of Primary Biliary Cholangitis?

This condition can lead to liver cirrhosis, portal hypertension, and in some cases, liver failure.

Can diet and lifestyle changes help manage Primary Biliary Cholangitis?

Making dietary changes and incorporating regular exercise can support overall health, but medical treatment is necessary.

What medications are used to treat Primary Biliary Cholangitis?

Ursodiol and Obeticholic Acid are commonly prescribed to manage this condition.

Are there any alternative therapies for Primary Biliary Cholangitis?

While some individuals explore complementary therapies, it's important to consult healthcare professionals before trying alternative treatments.

Can pregnancy affect Primary Biliary Cholangitis?

Pregnancy can pose risks for women with this condition, so it's crucial to seek medical guidance before planning a pregnancy.

How does Primary Biliary Cholangitis progress over time?

The disease progresses slowly, but in some cases, it can lead to liver complications and the need for transplantation.

What should I discuss with my doctor if I have been diagnosed with Primary Biliary Cholangitis?

Discuss treatment options, potential medication side effects, and the importance of regular monitoring with your healthcare provider.

Why is early detection of Primary Biliary Cholangitis important?

Early detection allows for timely intervention and can help slow down the progression of the disease.

Is there ongoing research for new treatments for Primary Biliary Cholangitis?

Yes, research continues to explore new therapies and treatment approaches for this condition.

What should I do if I experience worsening symptoms of Primary Biliary Cholangitis?

Contact your healthcare provider immediately to discuss any concerning changes in symptoms.

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